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Nolvadex is an antiestrogen medication used to decrease the risk of developing breast cancer in women with high risk of developing one, and in women with ductal carcinoma in situ (DCIS) after radiation or surgery. The medication is also used as a part of combination therapy for treating different types of breast cancer, as well as for treatment of breast cancer spread to other sites in the body. Nolvadex acts by blocking the effect of estrogen in some tumors (those activated by estrogen), preventing their growth.
Before starting to use Nolvadex it is recommended to read carefully (and re-read periodically) the directions for its administration. Take the medication with or without food at the same time every day, swallowing the pill wholly, without breaking or crushing it. Make sure not to miss your doses. If you, nevertheless, did, do not take two doses at once or with a too short interval.
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Nolvadex does not prevent from becoming pregnant. You should not become pregnant while using the medication as well as for two months after you stop taking it. The effectiveness and safety of Nolvadex in children have not been confirmed.
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As side effects of using Nolvadex, women may develop cancer of the uterus, blood clots in the lung, and stroke. In case you develop any of the following symptoms, contact your doctor right away: severe allergic reaction; abnormal menstrual period; unusual vaginal discharge or bleeding; groin pain or pressure; shortness of breath; chest pain; coughing up blood; one-sided weakness; speech or vision problems; confusion; skin changes; yellowing of the skin or eyes. Nolvadex may weaken your immune system, making you more subject to getting infected with colds and other infections.
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Competitively binds to estrogen receptors in target organs, like estrogen receptor translocates with the nucleus of tumor cells and thus blocks the action of estrogen.
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film-coated tablets 10 mg or 20 mg ; contour cell pack 10 pack cardboard 3 ;
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Competitively binds to estrogen receptors in target organs, like estrogen receptor translocates with the nucleus of tumor cells and thus blocks the action of estrogen.
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Contraindicated in pregnancy ( pre-treatment pregnancy must be excluded ) .
cialis At the time of treatment should stop breastfeeding ( not known whether tamoxifen in breast milk).
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Cardio- vascular system and blood (blood, hemostasis ) thrombophlebitis, thromboembolism, transient leukopenia, thrombocytopenia.
From the digestive tract. abdominal pain, nausea, vomiting, loss of appetite, constipation, increased liver enzymes, severe liver (cholestasis, hepatitis) .
Genitourinary. bleeding or vaginal discharge, amenorrhea, or irregular menstruation in premenopausal patients, the occurrence of reversible cystic ovarian tumors, fluid retention, itching in the genital area .
Allergic reactions. skin rash .
Other. alopecia, pain in the area of the lesion and / or bone, increasing the size of soft tissue structures ( accompanied by severe erythema lesions and surrounding areas ), hypercalcemia, hot flashes, increased body temperature, with prolonged use - cases of endometrial changes including hyperplasia polyps, intrauterine fibroids and in rare cases - endometrial cancer .
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Inside, in breast cancer - 20-40 mg / day (for 1 or 2 doses).
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